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Pain is an unpleasant experience like pinching, throbbing, stabbing, aching and tells you something may be wrong. Sometimes, it's just a nuisance, like a mild headache. This medication is used to relieve from moderate to severe pain. Synthetic substances such as Tramadol which are derived from opium poppy are considered to be opiates as well. Furthermore, Tramadol is not a narcotic pain medication.
Mechanism of action
ULTRAM is a synthetic opioid which is a centrally acting analgesic. Tramadol works by changing the perception way from the brain to the body. Specifically, tramadol inhibits both serotonin and nor epinephrine reuptake and activates opiate receptors in the central nervous system to enhance the inhibitory effects on pain transmission in the spinal cord.
Dosage and administration
· The Ultram should be started with 25 mg per day and reach to 100 mg per day by increasing 25 mg increments as separate doses every 3 days to reach 100 mg per day (25 mg, 4 times a day). Likewise the dosage regimen in case of 50 mg, the total daily dose may be increased every 3 days to reach 200 mg per day (50 mg, 4 times a day).
· Maximum Dose: Ultram 50 to 100 mg can be taken as needed for pain relief every 4 to 6 hours not to exceed 400 mg per day.
· In general, doses greater than 450 mg in one day can cause serious health problems, including seizures and serotonin syndrome.
How to use
v Before you start taking tramadol, read the medication Guide provided by your pharmacist.
v Take this medication by mouth or as directed by your doctor, usually every 4 to 6 hours as needed for pain relief.
v Peak level of tramadol occurs after 2 hours followed by a 100 mg oral dose. Several clinical studies state that the onset of pain relief was faster when taken in a combination formula of tramadol hydrochloride and acetaminophen (brand name Ultracet) as compared to Tramadol alone and also the onset of analgesia (pain relief) occurred in less than one hour.
Before taking this medicine
You should not take Ultram if you are allergic to tramadol, or if you have:
- Blockage in your stomach or intestines;
- Breathing problems such as severe asthma;
- If you have recently used sedatives, alcohol, tranquilizers or
- If you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, phenelzine, rasagiline).
Also some Side effects associated with Ultram 100mg include nausea, vomiting, itching, dizziness, headache, constipation, diarrhea and flushing (warmness, redness, or tingly feeling).
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